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  Product Name Rhodamine B-[(phenanthren-9-yl)-aminocarbonyl]-benzylester (RPAC)  
 
 graphch/ME046.gif  
 
Product Specifications 
 
 catalogue no.ME046 
 chemical nameRhodamine B-[(phenanthren-9-yl)-aminocarbonyl]-benzylester (RPAC)-
 
 IUPAC name6-(diethylamino)-N,N-diethyl-9-[2-({[4-(phenanthren-
9-ylcarbamoyl)benzyl]oxy}carbonyl)phenyl]-3H-xanthen-
3-iminium bromide
 
 synonymsRPAC 
 molecular formulaC50H46BrN3O4 
 molecular weight [g/mol]832.8219 (752.9174+79.9045)  
 CAS[ - ] 
 purity97%+ 
 categoryMedchem Compounds 
 melting pointn.d. 
 boiling pointn.d. 
 appearancepurple solid 
 solubilityDMSO 
 long term storage+4oC, stored dry and protect from light 
 Spectra1-H NMR 
 NMR analytics500 MHz (CDCl3) 
 
 Safety Information 
 
 R-sentenceR: 36/37/38 
 S-sentenceS: 26-24/25 
 hazardous substance symbolXn 
 safety infoCaution, substance not fully tested. Potential health effects. 
 
 References 1. Selective determination of mitochondrial chelatable iron in viable cells with a new fluorescent sensor. F. Petrat et. al. Biochem. J. (2002) 362, 137-147

2. Cold-induced apoptosis of hepatocytes: mitochondrial permeability transition triggered by nonmitochondrial chelatable iron; U. Rauen et al. Free Radical Biology & Medicine, Vol. 35, No. 12, pp. 1664-1678, 2003

3. The chelatable iron pool in living cells: A methodically defined quantity. F. Petrat et. al. Biol. Chem., Vol. 383, pp. 489-502, 2002

4. Assessment of chelatable mitochondrial iron by using mitochondrion-selective fluorescent iron indicators with different iron-binding affinities. U. Rauen et al. ChemBioChem 2007, 8, 341-352

5. Oxidative inactivation of mitochondrial Aconitase results in iron and hydrogen peroxide-mediated neurotoxicity in rat primary mesencephalic cultures. David Cantu et. al. PlosOne, September 2009, Vol 4, Issue 9, p 1-9
 
 
 Application Notes  
  RPAC is used in the same manner as RPA. 1-5 mM stock solutions of RPAC in DMSO can be prepared and aliquots should be kept at -20oC. When stored properly at -20oC, the frozen aliquots are stable and can be used for at least 2-3 months. 
 
 Ordering Information  
 
 
Cat. No. | Product Name | Quantity | Price  
 
ME046.1   Rhodamine B-[(phenanthren-9-yl)-aminocarbonyl]-benzylester (RPAC)   1 mg   240,- €  
ME046.2   Rhodamine B-[(phenanthren-9-yl)-aminocarbonyl]-benzylester (RPAC)   5 mg   725,- €  
 
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