| |
|
|
|
|
|
|
|
|
|
|
|
|
|
| mAb to O6-methyl-2-deoxyguanosine (EM 2-3) |
| |
| |
Product Data |
|
Graphics |
|
Product Flyer |
|
References |
|
|
|
|
|
|
| |
| |
|
|
|
|
|
| Request info |
| |
| |
|
|
| |
Product Name |
mAb to O6-methyl-2-deoxyguanosine (EM 2-3) |
|
| |
Synonyms |
EM 2-3 monoclonal antibody |
|
| |
Catalog No |
SQM003.1 |
|
| |
Size |
100 µg |
|
| |
Price |
425,00 EUR |
|
| |
Category |
Antibodies and Conjugates |
|
| |
Description |
monoclonal antibody, specific for O6-methyl-2-deoxyguanosine |
|
| |
Background |
DNA-lesion specific monoclonal antibody |
|
| |
Feature |
Detects a specific mutagenic DNA modification induced by several exogenous and endogenous carcinogens e.g. food, smoking, cancer therapeutics, environmental carcinogens, workplace carcinogens; Molecular epidemiology of carcinogen exposure; Pre- and intratherapeutic dosimetry of exposure to anticancer agents; Basic research of molecular mechanisms of carcinogenesis; Mutagenicity testing of substances |
|
| |
Appearance |
160 kDa |
|
| |
Reconstitution |
lyophilized |
|
| |
Stabilizer |
reconstitute with 1 ml of PBS, 0.05% sodium azide, 1% bovine serum albumine |
|
| |
Storage |
none |
|
| |
Conjugate/Tag/Label |
-20°C |
|
| |
Use |
competitive radioimmunoassay; ELISA; Immunoaffinity/Quantitative PCR; Immunocytochemistry: 0.05 - 0.2 µg/ml PBS containing 3% bovine serum albumin |
|
| |
Host |
specifically reacts with O6-methyl-2-deoxyguanosine in human, mouse, rat, hamster |
|
| |
Isotype |
mouse |
|
| |
Clonality |
IgG1 |
|
| |
Clone |
monoclonal |
|
| |
Immunogen |
EM 2-3 |
|
| |
Specificity |
O6-methyl-2-deoxyguanosine-Thyroglubulin conjugate |
|
| |
Cross Reactions |
O6-methyl/ethyl/butyl-2-deoxyguanosine |
|
| |
Affinity Constant |
in immunocytochemistry the antibody crossreacts efficiently with O6-ethyl-2-deoxyguanosine and O6-butyl-2-deosyguanosine |
|
| |
Purification |
4.4 x 10 e8 (l/Mol) |
|
| |
Concentration |
Protein G affinity purification from cell culture supernatant |
|
| |
Activity |
>95% |
|
| |
Source |
test dependent |
|
| |
Considerations for Use |
1 year |
|
| |
Additional Info |
Please store the vial at 4-8 deg. C. The product is stable for 1 year at 4-8 deg. C in its stock solution. Working dilutions should always be prepared freshly. For extended storage of the stock solution please add 50% glycerol and freeze the product. |
|
| |
