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mAb to 3-ethyl-adenine (EM 6-47)
 
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  Product Name mAb to 3-ethyl-adenine (EM 6-47)  
  Synonyms EM 6-47 monoclonal antibody  
  Catalog No SQM013.1  
  Size 50 µg  
  Price 375,00 EUR  
  Category Antibodies and Conjugates  
  Description monoclonal antibody, specific for 3-ethyl-adenine  
  Background DNA-lesion specific monoclonal antibody  
  Feature Detects a specific mutagenic DNA modification induced by several exogenous and endogenous carcinogens e.g. food, smoking, cancer therapeutics, environmental carcinogens, workplace carcinogens; Molecular epidemiology of carcinogen exposure; Pre- and intratherapeutic dosimetry of exposure to anticancer agents; Basic research of molecular mechanisms of carcinogenesis; Mutagenicity testing of substances  
  Appearance 160 kDa  
  Reconstitution lyophilized  
  Stabilizer reconstitute with 0.5 ml of PBS, 0.05% sodium azide, 1% bovine serum albumine  
  Storage none  
  Conjugate/Tag/Label -20°C  
  Use Competitive Radioimmunoassay, ELISA  
  Host specifically reacts with 3-ethyl-adenine in human, rat  
  Isotype mouse  
  Clonality IgG1  
  Clone monoclonal  
  Immunogen EM 6-47  
  Specificity 3-ethyl-adenine-Thyroglubulin conjugate  
  Cross Reactions 3-ethyl-adenine  
  Affinity Constant see RIA specifity table (see graphics)  
  Purification 4.7 x 10 e9 (l/Mol)  
  Concentration Protein G affinity purification from cell culture supernatant  
  Activity >95%  
  Source test dependent  
  Considerations for Use 1 year  
  Additional Info Please store the vial at 4-8 deg. C. The product is stable for 1 year at 4-8 deg. C in its stock solution. Working dilutions should always be prepared freshly. For extended storage of the stock solution please add 50% glycerol and freeze the product.  
 
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