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Product Data |
| | mAb to 8-oxo-2-deoxyguanosine (EM 8oxo-4) |
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Product Name |
mAb to 8-oxo-2-deoxyguanosine (EM 8oxo-4) |
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Synonyms |
EM 8oxo-4 monoclonal antibody |
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Catalog No |
SQM021.1 |
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Size |
100 µg |
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Price |
375,00 EUR |
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Category |
Antibodies and Conjugates |
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Description |
monoclonal antibody, specific for 8-oxo-2-deoxyguanosine |
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Background |
DNA-modification specific monoclonal antibody |
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Feature |
Detects a specific mutagenic DNA modification induced by several exogenous and endogenous sources e.g. UV-light, radiation, dusts, diesel exhaust, inflammations, food, smoking, cancer therapeutics, environmental carcinogens, workplace carcinogens;
Molecular epidemiology of exposure;
Pre- and intratherapeutic dosimetry of exposure to anticancer agents;
Basic research of molecular mechanisms of carcinogenesis;
mutagenicity testing of substances |
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Appearance |
160 kDa |
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Reconstitution |
lyophilized |
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Stabilizer |
reconstitute with 1 ml of PBS, 0.05% sodium azide, 1% bovine serum albumine |
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Storage |
none |
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Conjugate/Tag/Label |
-20°C |
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Use |
Competitive Radioimmunoassay, ELISA; antibody may not be suitable for immunohistochemical staining |
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Host |
specifically reacts with 8-oxo-2-deoxyguanosine |
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Isotype |
mouse |
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Clonality |
IgG1 |
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Clone |
monoclonal |
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Immunogen |
EM 8oxo-4 |
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Specificity |
8-oxo-2-deoxyguanosine-Thyroglubulin conjugate |
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Cross Reactions |
8-oxo-2-deoxyguanosine |
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Affinity Constant |
see RIA specifity table (see graphics) |
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Purification |
8.4 x 10 e6 (l/Mol) |
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Concentration |
Protein G affinity purification from cell culture supernatant |
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Activity |
>95% |
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Source |
test dependent |
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Considerations for Use |
1 year |
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Additional Info |
Please store the vial at 4-8 deg. C. The product is stable for 1 year at 4-8 deg. C in its stock solution. Working dilutions should always be prepared freshly. For extended storage of the stock solution please add 50% glycerol and freeze the product. |
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| Squarix GmbH - Elbestraße 10 - D-45768 Marl - Germany |
| fon: +49-2365-20400-0 - fax: +49-2365-20400-60 - www.squarix.de - e-mail: info@squarix.de |