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T3 - Horseradish Peroxidase Conjugate
 
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  T3-HRP  Cat. No. T3HRP.1 (1 mg)
Cat. No. T3HRP.2 (5 mg)
Cat. No. T3HRP.3 (10 mg)
 
 
T3 - Horseradish Peroxidase Conjugate  
 
  t3_hrp.gif    
 
  L-Thyroxine - enzyme conjugate with horseradish peroxidase  
  Reagent for T3 ELISA with commonly used anti T3-antibodies  
  High activity    
  Improved stability    
 
  Product Data    
 
  Product name T3-HRP  
  raw material horseradish peroxidase type VI-A  
  activity 1500 U/mg solid  
  label T3 (Triiodothyronine)  
  quantity 1 mg / 5 mg / 10 mg  
  conjugation ratio POD/T3:  1:1  
  purity > 99% (HPLC)  
  form lyophilised, essentially salt free  
  reconstitution 1 ml PBS without azide (T3HRP.1)
5 ml PBS without azide (T3HRP.2)
10 ml PBS without azide (T3HRP.3)
 
  working dilution (ELISA) 1:5000 - 1:10000  
  storage -20°C, dry  
  usage For research use only. Not intended for diagnostic use. Suitable for use in immunoassay development or other applications.  
  keywords thyroxine; T4; T3; thx; thyroxinal; Thyrax; Henning; tetraiodothyronine, triiodothyronine, diiodophenyl-L-alanine; DL-thyroxine, T3-HRP, T3-POD  
 
  Information    
 
  The thyroid hormones, triiodothyronine (T3) and thyroxine (T4), are tyrosine-based hormones produced by the thyroid gland that are primarily responsible for regulation of metabolism. Iodine is necessary for the production of T3 and T4. A deficiency of iodine leads to decreased production of T3 and T4, enlarges the thyroid tissue and will cause the disease known as goitre. The major form of thyroid hormone in the blood is thyroxine (T4), which has a longer half-life than T3. The ratio of T4 to T3 released into the blood is roughly 20 to 1. T4 is converted to the active T3 (three to four times more potent than T4) within cells by deiodinases (5'-iodinase). These are further processed by decarboxylation and deiodination to produce iodothyronamine (T1a) and thyronamine (T0a). All three isoforms of the deiodinases are selenium-containing enzymes, thus dietary selenium is essential for T3 production.  
 
  References    
 
  1)  Kirkegaard C, Faber J (1998). "The role of thyroid hormones in depression". Eur J Endocrinol 138 (1): 1-9.  
  2)  Dratman M, Gordon J (1996). "Thyroid hormones as neurotransmitters". Thyroid 6 (6): 639-47.  
 
 Ordering Information  
 
 
  Cat. No. | Product Name | Quantity | Price*  
  T3HRP.1   thyroxine T3 - horseradish peroxidase conjugate   1 mg   395,00 EUR  
  T3HRP.2   thyroxine T3 - horseradish peroxidase conjugate   5 mg   1.545,00 EUR  
  T3HRP.3   thyroxine T3 - horseradish peroxidase conjugate   10 mg   2.295,00 EUR  
    * For bulk package size please inquire. Prices do not contain shipping costs, please inquire. Last updated: June 06 2023  
 
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